How would you treat a patient with a low grade Follicular lymphoma and Gleason 6 adenocarcinoma of the prostate?

There are too many unstated particular clinical parameters to provide a specific answer to this question, but general principles are that neither of these malignancies necessarily require intervention. The very long natural history of each condition should guide us.

Stage, symptoms, functional status, and particular anatomy of the lymphoma might lead to advising involved site radiation (ISRT).

Particular details regarding age, functional status, genetics, staging, and PSA trend might conceivably lead to consideration of intervention for the prostate cancer, for which radiation is one of the options, though there are few Gleason 6 cancers that obligate any intervention.

If, by chance, this question was intended to describe follicular lymphom...