How would you treat a patient with a post prostatectomy biochemical and pelvic nodal recurrence with a BLM mutation?

Full disclosure: I have never treated a patient, or been referred a patient for treatment, who I knew had a BLM mutation. For the sake of this discussion, I will assume that the patient in question has Bloom syndrome and is not just a carrier with a mutation in only one copy of the gene. The syndrom...