How would you treat a patient with metastatic NSCLC >50% PDL-1 positive AND an EGFR or ALK gene mutation/rearrangement in the first-line setting?   

1st-line pembrolizumab is supposed to be used AFTER failure of appropriate targeted agents in this setting, but would you consider the reverse sequence in some patients?



Answer from: Medical Oncologist at Academic Institution
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Medical Oncologist at Yuma Regional Medical Center Cancer Center
Would you add immunotherapy to 2L chemotherapy in ...
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Answer from: Medical Oncologist at Academic Institution