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Topics:
Genitourinary Cancers
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Medical Oncology
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Renal Cell Carcinoma
How would you treat a patient with metastatic sarcomatoid renal cell carcinoma after progression on Nivolumab and Cabozantinib?
What is your preferred first and second line treatment regimen?
Related Questions
Is there still a role for mTOR inhibitors in metastatic RCC in the immunotherapy/TKI era?
When, if ever, would you re-challenge with immunotherapy for patients with metastatic RCC?
Would you use adjuvant pembrolizumab for bilateral ccRCC with R1 resection?
In a patient with metastatic RCC who discontinued nivolumab after a prolonged response to ipilimumab/nivolumab, would you consider re-starting nivolumab at disease progression?
What is your treatment approach in localized RCC with VHL mutation after progression on belzutifan?
Would the occurrence of obvious tumor rupture/spillage intraoperatively impact your decision for adjuvant systemic therapy after resection of either clear cell RCC or papillary RCC?
How would you approach the use of bevacizumab in metastatic FH-deficient RCC/HLRCC that is c/b extensive IVC tumor thrombus and DVT/PE?
How would you treat a patient with metastatic RCC with high grade neuroendocrine and sarcomatoid features after progression on IO + TKI?
Would you offer adjuvant immunotherapy in a patient with high risk RCC with new/worsening post-op renal dysfunction and CrCl<30?
How would you approach adjuvant systemic therapy for an isolated, oligometastatic CNS recurrence of RCC that was treated with SBRT?