How would you treat a patient with muscle invasive urothelial carcinoma with squamous differentiation?
What would your treatment approach be- surgery or chemoRT? What is your preferred chemo regimen?
Is there a % threshold other than 100% (e.g. 95%) that you would consider pure squamous rather than mixed histology?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · AdventHealth Cancer Institute
Answered on
In general, pure and predominant urothelial carcinoma (majority or >50% of tumor consisting of urothelial carcinoma) have been treated similarly at least in trials. Patients with predominant or pure non-urothelial histology have typically not been enrolled in trials of urothelial carcinoma. There ar...
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