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How would you treat a patient with necrotizing myopathy with positive anti-HMHCoR Ab unresponsive to standard therapies?

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Mednet Member
Mednet Member
Neurology · University of Minnesota

There are several questions raised by this scenario. I have personally never seen a patient with true HMGCR-antibody + necrotizing autoimmune myopathy fail a combination of 3 immunotherapies (high dose prednisone, IVIG, and either Rituximab or oral immunosuppression like Cellcept/azathioprine, etc),...

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How would you treat a patient with necrotizing myopathy with positive anti-HMHCoR Ab unresponsive to standard therapies? | Mednet