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How would you treat a stage I fully resected double hit DLBCL?

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What adjuvant chemotherapy would you offer for a fit, non-elderly patient with fully resected double hit Stage I DLBCL?

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1 Answer
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Medical Oncology · Mayo Clinic Jacksonville
Answered on

In patients with fully resected DLBCL, I still give chemotherapy. That also applies to double-hit lymphomas. Limited-stage DHL does not seem to have a poorer prognosis than non-DHL, and intensive regimens do not make a difference. I would treat with RCHOP x 3-4 cycles.

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