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How would you treat an elderly female with residual TNBC following surgery and neoadjuvant carboplatin and paclitaxel?

Assume normal cardiac function and no obvious co-morbidities. No anthracycline previously due to age alone. The patient’s BRCA status is unknown, but presumably negative given her age. She has not received capecitabine yet at this time.
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Answered on · Updated on

I think there will be some differing opinions on this. There are a number of things I would factor in, assuming the patient has enough life expectancy where the breast cancer is the main mortality risk.

1) Data from carbo/taxane neoadjuvant trials (Sharma et al., PMID 30061361) and others suggest RC...

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