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How would you treat an unresectable epithelioid angiosarcoma invading the cavernous sinus, wrapping around the carotid artery?
What dose/fractionation expansion would you recommend? Would you use concurrent taxane? (no mets on staging)
Answer from: Radiation Oncologist at Community Practice
Stage with PET and MRI. If any concern for intradural spread, complete spine imaging and consider LP to r/o LMD. Start with neoadjuvant taxane-based chemotherapy, potentially in a doublet (e.g., gem/tax). Then definitive CRT with concurrent taxol and conventional fractionation to 70 Gy, while respec...
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Answer from: Radiation Oncologist at Community Practice
Definitive RT using conventional fractionation to 66-70 Gy (respecting OARs) with concurrent taxane.