Topics:
Gastrointestinal Cancers • Medical Oncology
How would you treat metastatic squamous esophageal carcinoma that is HER2 negative?
Most oncologists are comfortable offering FOLFOX for 1st line metastatic adenocarcinoma. Would you be comfortable offering FOLFOX to met. squamous esophageal as well?
Answer from: Medical Oncologist at Academic Institution
In general we would not check HER2 status in squamous cell tumors of the esophagus. I think FOLFOX would be a reasonable first line regimen. Others would be cisplatin with 5FU. There is no standard of care first line regimen. Another reasonable option would be carboplatin with paclitaxel.
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