How would you treat non-secretory myeloma in an inpatient setting?
Does your management change based on the type of end-organ involvement at the time of diagnosis?
Are there any reports of CNS involvement with non-secretory myeloma?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · University of Miami
Answered on
This entity is rare with the use of free light chain assay. About 2% of all cases are non-secretory. In A Greek study, they were younger, less anemic, and had less often renal dysfunction and less extensive bone marrow infiltration. Presence and extent of bone disease were similar, however, hypercal...
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Mednet MemberInvited Expert
Medical Oncology · University of Kansas Medical Center
Answered on
Let me break up the question into the following scenarios as I am assuming the patient is newly diagnosed:
- If the patient is Newly diagnosed Non-secretory myeloma (NDNSMM (no end organ damage), I will consider treatment outpatient with a possibility to bridge him with pulse dexamethasone until PT...
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