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How would you treat recurrent endometrial carcinoma with a presentation of inguinal and external iliac adenopathy?

Re-staging is otherwise negative; patient's disease has FIGO grade 1 endometroid histology
3 Answers
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

I would treat with definitive intent with either surgery followed by (chemo) RT or definitive (chemo) RT targeting the pelvic at least up to the common iliac and bilateral inguinal region.

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Radiation Oncology · Vanderbilt-Ingram Cancer Center
Answered on

Presumable post-surgical recurrence without receipt of previous RT. Is there a vaginal recurrence as well in or extending to the distal vagina, which could explain the inguinal nodes? Are the nodes PET-positive or biopsy-proven?

If this is purely a nodal recurrence, no reason to think distal vaginal...

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Radiation Oncology · Allegheny Health Network
Answered on

If not already done, I would get PET/MRI and do an EUA with gyn onc to rule out vaginal recurrence as @Dr. First Last noted.

Then I would treat with definitive intent RT with chemo if able. I would follow that with carbo taxol if tolerable +- IO with consideration of MMR status.

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