How would you treat someone with unknown primary metastatic SMARCA4 deficient tumor (high-grade tumor with rhabdoid morphology)?

2 Answers

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Medical Oncology · The Ohio State University Comprehensive Cancer Center

Answered on

Ponatinib might be useful. You might also see if a clinical trial is available.

http://clincancerres.aacrjournals.org/content/24/8/1932

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Medical Oncology · Oregon Health & Science University

Answered on

Consider tazemetostat (epigenetic modifier via EZH2 nhibition) via compassionate use program.

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