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Topics: Pediatric Hematology/Oncology • Internal Medicine • Rheumatology • Hematology • Pediatric Hematology • Benign Hematology • Allergy & Immunology • Dermatology • Mastocytosis • Mast Cell Disorders

How would you work up a patient with cutaneous mastocytosis?  

Is a BM biopsy a must when there is skin involvement?

If tryptase level is mildly elevated but less than 20 would you recommend a BM biopsy?



Answer from: Medical Oncologist at Academic Institution
Is a BM biopsy a must when there is skin involvement? I think a bone marrow biopsy for cutaneous mastocytosis is most helpful when it is in the setting of a patient being referred by dermatology for a skin biopsy result showing TMEP (telangiectasia macularis eruptive perstans) since TMEP has be...
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