Dermatology
Clinical insights on skin conditions, dermatologic procedures, and treatment approaches from practicing dermatologists.
Recent Discussions
When do you recommend SRT, if ever, for small SCCs and BCCs?
SRT is a highly effective treatment for superficial radiation therapy. What is alarming is the use of daily US guidance for something we can visualize with our eyes. With electrons, I’ve never heard of anyone using image guidance. With SRT, the request for daily image guidance is routinely requested...
Do you routinely prescribe oral antifungals for seborrheic dermatitis?
The most common indication when I have prescribed an oral anti fungal is when the seborrheic dermatitis extends beyond the scalp, such as on the sternum and/or face (petaloid), and has failed topicals. With that much widespread distribution, adequate application of topical treatments can be very cha...
Do you recommend a workup for POEMS and/or amyloidosis for IgM monoclonal gammopathies associated with neuropathy?
While IgM monoclonal disorders, amyloidosis, and POEMS syndrome may all be associated with peripheral neuropathy, they are not often confused with one another. A patient with a peripheral neuropathy can be diagnosed most simply by a serum protein electrophoresis. The presence of a monoclonal IgM spi...
What are your recommendations in managing pudendal neuralgia/red scrotum syndrome?
Red scrotum syndrome is very challenging to treat. The list of reported treatments is long, but I have not found one to be consistently effective. Treatment selection depends significantly on patient characteristics and preferences. In my opinion, every patient with red scrotum syndrome should under...
Is there an age cut off below you would not treat a keloid with radiation post surgical excision?
While radiotherapy is considered an extremely useful modality in the treatment of recurrent keloids in the adult population, most would contend that the risks do not justify the application of adjuvant radiotherapy in the pediatric population (Botwood et al., PMID 10703484) for a benign condition wh...
In patients with hidradenitis suppurativa, are there any specific clinical scenarios where you still hold biologics prior to deroofing or wide local excision for persistent sinus tracts?
I am more concerned about HS flaring with biologic discontinuation than I am about the risks of infection or poor wound healing from the biologic. I cannot think of a scenario where I would hold the biologic for de-roofing or excision.
What laboratory workup do you perform in patients with symptoms consistent with erythromelalgia?
The usual CBC with differential, as well as CRP, ANA, ESR, and Rheumatoid Factor.
How do you manage atopic dermatitis in patients who have failed dupilumab?
The therapeutic landscape for atopic dermatitis is being updated every year, meaning that this question will have different answers in the next few years. In fact, new guidelines are being updated more frequently to capture new drug approvals. As always, medication selection should weigh risks and b...
What oral treatment options would you offer a patient with severe onychomycosis who is also on methotrexate for another condition?
I prefer pulsed terbinafine at 250 mg daily x1 week every other month. Dr. Zaias showed in a comparative study that pulsed terbinafine works as well as giving it daily for 3 months, and since the patient is only taking this for 1 week every other month, risks for hepatotoxicity are minimal.
Do you recommend checking anti-drug antibodies for patients on TNF inhibitors?
This is a very good question with direct clinical practice implications. I do not check or follow anti-drug antibodies when using TNF inhibitors for the treatment of rheumatoid arthritis or psoriatic arthritis. There are reports that suggest, on a group level, that these antibodies, if present, impa...