How would you work up and manage an isolated CN3 deficit with anisocoria?

MRI Orbits with possible mild enhancement of unilateral CN3; Brain MRI chronic microvascular disease, mild atrophy.

Answer from: at Academic Institution

This question proposes an isolated CN 3 deficit, with almost no other clinical information. (Just as an aside, it would be important to note whether there is any evidence of aberrant regeneration of CN 3 and also check to make sure that there is no involvement of CN 4, which would immediately shift...

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at National Institute of Neurological Disorders and Stroke (NINDS) National Institutes of Health (NIH)
Thanks for the answer, 80+-year-old CF, no signif...

at Georgetown University
Oh, so no eye movement abnormailty? Isolated mydri...

Answer from: at Academic Institution

This is an interesting question and of course, depends on how "complete" the Cranial Nerve III is. The above differential diagnosis is excellent: "If there is no evidence of any structural lesion, then I would consider the possibility of inflammatory, infectious, or ischemic etiologies for the CN 3 ...

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at Georgetown University
Yes, I would consider a "diabetic third nerve pals...

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How would you work up and manage an isolated CN3 deficit with anisocoria?

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