If a patient who has previously been taking lamotrigine stops taking it for between two weeks and a month, do you have to uptitrate it all over again or do you have another way to resume it?

I'm not aware of good data to answer this question. To be safest, I would probably titrate again at the usual schedule as though starting from scratch. In the epilepsy monitoring unit, we're typically comfortable with restarting at-home doses without retitrating up to 14 days off meds (the lower lim...