If a stage I laryngeal cancer completely responds to FU-based chemotherapy (given for another malignancy) would you consider observation?
Answer from: Radiation Oncologist at Community Practice
We expect 60-80% response rate with induction chemo data with 20% having complete response. That doesn’t preclude local treatment but predicts for better outcome
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Answer from: Radiation Oncologist at Community Practice
Holding RT and following early stage laryngeal cancer seems like a risky proposition. You have a high likelihood of a favorable outcome with microscopic residual disease treated with small field definitive radiotherapy. The late toxicities are low with RT for early glottic cancer and it’s a re...
Radiation Oncologist
2019-03-03 Addendum: 10 yr update of Univ. Paris results using CTX alone for N0M0 larynx and pharynx SqCCa. Please see new reference below.Laccourreye, O et al. Ten-year outcome of curative "exclusive" chemotherapy in N0M0 SqCCa of the larynx and pharynx with complete clinical response. Head and Nec...
Comments
Radiation Oncologist at Boston Medical Center, Boston University School of Medicine
I agree with comments made by Bruce Greene- it dep...
I agree with comments made by Bruce Greene- it dep...
Medical Oncologist at NYU Winthrop Hospital
I will recommend definitive Radiation.
I will recommend definitive Radiation.
Answer from: Radiation Oncologist at Community Practice
No. I would irradiate. Jim Parsons (UF alumni) used to say a "CR is only half way to a C-U-R-E."