If a stage I laryngeal cancer completely responds to FU-based chemotherapy (given for another malignancy) would you consider observation?
Answer from: Radiation Oncologist at Community Practice
We expect a 60-80% response rate with induction chemo data, with 20% having a complete response. That doesn’t preclude local treatment but predicts for better outcome.
Answer from: Radiation Oncologist at Community Practice
Holding RT and following early stage laryngeal cancer seems like a risky proposition. You have a high likelihood of a favorable outcome with microscopic residual disease treated with small field definitive radiotherapy. The late toxicities are low with RT for early glottic cancer and it’s a re...
2025-12-04 Addendum: Additional long term data from MDAH on CTX alone in Stage II-IVa laryngeal SqCCa. Ref. below.Trinconi Cunha, M et al. Chemotherapy Alone for Stage II-IVa laryngeal squamous cell carcinoma: A 20-year follow up. Cancer 2025;131(23) 2019-03-03 Addendum: 10 yr update of Univ. P...
Comments
Radiation Oncologist at Boston Medical Center, Boston University School of Medicine I agree with comments made by Bruce Greene- it dep...
Medical Oncologist at NYU Winthrop Hospital I will recommend definitive radiation.