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If an ulcerative colitis patient has a 90 percent response to a biologic or small molecule after over 12 months, would you consider switching medication to a different class in hopes of getting a complete response, versus trying adjunctive therapy?

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Mednet Member

Gastroenterology · Mayo Clinic

I am not sure what you mean by “90%” response. Is that clinical, laboratory, or endoscopic? Perfection is the enemy of good, so you'd better have a compelling reason to make a patient add another therapy.