If neoadjuvant therapy is indicated for luminal A breast cancer, when do you decide to use chemotherapy versus endocrine therapy?

Are there particular patient characteristics (e.g. age, ER%, Ki67, grade) that make you more likely to choose neoadjuvant endocrine therapy?

1 Answer

Mednet Member

Medical Oncology · Northwestern Medicine Cancer Center at KishHealth

Answered on

My practice is to perform recurrence risk assay on biopsy specimen and decide on the choice of neoadjuvant therapy (chemo vs anti estrogen). A clear indication for chemotherapy would not require a recurrence risk assay.

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