In a breast cancer patient treated with neoadjuvant endocrine therapy, how would the presence of a lymph node micrometastasis influence your recommendations regarding radiation therapy?

Data free zone but that being said, since the likelihood of PCR is low (not like triple negative or HER2 negative), I usually don’t necessarily add RNI. For BCT, treat with tangent including level 1 and 2 nodes.

For mastectomy, look at other risk factors (pre and post ET) to see if would offer PMRT.