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In a patient with metastatic breast cancer who has progressed on multiple medications and has now developed multiple brain metastases, what is your radiotherapy plan if the patient is taking sacituzumab govitecan?

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Mednet Member
Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network

The limited published data have not shown increased complications with SRS along with sacituzumab, unlike increased necrosis seen with HER2/neu antibody conjugate.

Khatri et al., PMID 41026418

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