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In a patient with brain metastasis confined to the cerebellum, would it be reasonable to treat the posterior fossa only (vs WBRT)?

What are the best options to treat a patient with brain metastasis confined to the posterior fossa if the patient is young, has a favorable cancer, great KPS status and would like to avoid the memory loss associated with WBRT?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Columbia University Irving Medical Center
Answered on

If the patient has favorable prognostic factors and would like to avoid memory loss associated with WBRT, I would first consider whether the patient is eligible for stereotactic radiosurgery. If not a candidate for stereotactic radiosurgery, I would consider enrollment on eligible hippocampal avoidance whole brain radiotherapy trials. If not a candidate I would consider whole brain radiotherapy. My concern would be the need to reirradiate the supratentorium in the future and risk of radiation ov...

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