In a patient with eosinophilic asthma that is controlled daily in between exacerbations, but has very symptomatic exacerbations which lead to ER visits and steroid bursts about 2 to 3 times per year, would you consider starting a biologic agent for prevention of exacerbations even though outside of flares patient is controlled?

1 Answers

Mednet Member

Allergy & Immunology · University of Washington School of Medicine

A pragmatic approach to a patient like this is consideration of SMART (Single Maintenance And Reliever Therapy) with a single inhaler containing inhaled corticosteroid (ICS) and formoterol.

Although controlled most of the time, the exacerbation profile suggests suboptimal control of inflammation at ...