In a patient with liver metastases from a pancreatic NET, that have been successfully treated with ablation by interventional radiology, would you resect the primary pancreas lesion?

Grade absolutely matters here. The number of liver mets and other extent of disease also matter. For low-grade pancreatic neuroendocrine tumors (PNET) with liver only metastases who are good candidates for surgery, resection can be considered. Benefit was seen in this study with locally advanced PNE...