In a patient with very advanced head and neck cancer treated with induction chemotherapy and then definitive radiation do you recommend adding concurrent chemotherapy with the radiation?
After initial induction chemo, how do you choose between radiation alone or concurrent CRT?
Answer from: Medical Oncologist at Academic Institution
Sequential chemotherapy does not provide a survival benefit over definitive chemoradiation. [1], [2], [3]. Hence, reasons to consider induction chemotherapy are for local control of disease and to delay the onset of distant metastases. Additionally, there are concerns for increased toxicity and dela...
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Answer from: Radiation Oncologist at Academic Institution
Yes