Topics:
Hematologic Malignancies • Radiation Oncology • Medical Oncology • Myeloma • Waldenstrom • Hematology
In a patient with Waldenstrom's macroglobulinemia doing well and feeling better on ibrutinib & rituximab, but with a rising IgM, do you switch treatment or continue?
Answer from: Medical Oncologist at Academic Institution
A lot depends on the pace of increase of the IgM and the line of therapy. If the pace is rapid, I would think about changing therapy. If the pace of increase is small and the patient is asymptomatic, you could continue a little longer. If planning to changing therapy, it may be reasonable to restage...
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