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Topics:
Hepatology
•
Autoimmune Liver Disease
In a serologic evaluation for immune-mediated liver disease, what further workup do you pursue when low immunoglobulins are identified?
Related Questions
How do you prefer to manage IgG-4 related hepato-biliary disease, especially if there are similarities in imaging findings to other immune mediated liver diseases?
What is your strategy in the management of patients with autoimmune hepatitis who failed azathioprine therapy and what parameters do you monitor with what frequency?
In what clinical scenario do you initiate the use of ileal bile acid transport (IBAT) inhibitors in the management of cholestatic liver disease?
How will the recent withdrawal of Ocaliva for the treatment of PBC impact your therapeutic and management plan for these patients?
In AIH/PBC overlap with both hepatitis and cholestasis, how do you determine whether incomplete biochemical response at 6–12 months reflects undertreated AIH versus inadequately controlled cholestasis?
What early response criteria and timeframe do you use to declare corticosteroid non-response and move to expedited transplant listing in patient with acute severe AIH without encephalopathy?
What is your strategy to manage pruritus in patients with cholestatic liver disease?
For suspected drug-induced autoimmune-like hepatitis after the culprit drug is stopped and there is no advanced fibrosis, how do you decide immunosuppression duration and the relapse-free follow-up interval needed to confidently label it DI-ALH rather than classic AIH?
In what clinical scenario would you consider the use of budesonide over prednisone as part of the pharmacologic management of autoimmune hepatitis?
What is your approach to induction therapy and maintenance therapy for patients with autoimmune hepatitis?
