In a young male patient with hypogonadotropic hypogonadism and fertility goals, would starting testosterone replacement therapy affect fertility chances?

Men with hypogonadotropic hypogonadism due to congenital hypogonadotropic hypogonadism or acquired hypogonadotropic hypogonadism due to structural disease (e.g., a pituitary macroadenoma) typically require gonadotropin therapy to optimize spermatogenesis and fertility.

For men who have hypogonadotro...

In male obesity-associated hypogonadism clomiphene is effective in increasing T levels as well as in improving insulin sensitivity; this may be a good option at least for short term treatment of these men without affecting fertility. I have usually prescribed 25mg hs three times a week. See randomiz...