In addition to monitoring hemoglobin and supplementing folic acid, what is your approach to hereditary spherocytosis in pregnancy?
No prior transfusions needs.
Do you have a distinct hemoglobin target in pregnancy? Do you consider VTE prophylaxis? Do you obtain genetic testing to guide evaluation for fetal anemia and newborn hyperbilirubinemia?
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Do you routinely obtain genetic testing for pregnant women with known RBC membrane disorders?
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1 Answer
Mednet MemberInvited Expert
Hematology · University of Maryland
Answered on
I use the same transfusion threshold for the general pregnant population but I do refer to maternofetal medicine/high risk pregnancy clinic for closer fetal monitoring. My personal preference is to obtain genetic testing to confirm the specific mutation responsible for hereditary spherocytosis as it...
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