In cirrhosis with suspected HRS-AKI and baseline CKD or chronically elevated creatinine, how do you define a clinically meaningful ‘improvement’ during an albumin trial (over 24–48 hours) to distinguish HRS-AKI from volume-responsive AKI?
2 Answers
Mednet MemberInvited Expert
Hepatology · University of Toronto
Answered on
If the acute rise in serum creatinine returns to the pre-AKI level, the patient has volume-responsive AKI.
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Mednet MemberInvited Expert
Hepatology · Ochsner Health
Answered on
The guidelines define it as drop in serum creatinine within to 0.3 mg/dl of baseline creatinine.
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