In light of the recently published LAP07 trial, what is the role of radiation in unresectable pancreatic cancer?

The recent publication of LAP07 is welcome, as the results have been known since the data were presented at ASCO 2013, and my impression is that the results have already led to a reduction in the use of radiation for locally advanced pancreatic cancer. This may be appropriate, but the results need t...

I agree with most of the comments except for the commonly held believe that low-dose palliative SBRT in 5 fractions offers any hope of a different outcome in either LAPC or BRPC. Median survival from a very large number of single arm studies treating carefully selected LAPC patients with 25-33Gy in ...

I agree with @Dr. First Last's thoughts. Many will cite the results of this trial as indicating that there is no role for RT in locally advanced patients; I think there is a role in selected patients. However, we should be mindful that improved systemic control using regimens like FOLFIRINOX may inc...