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What duration of ADT do you recommend for patients with high risk or very high risk prostate cancer who undergo radical prostatectomy, adjuvant RT, and adjuvant docetaxel?

1 Answer
Mednet MemberInvited Expert
Medical Oncology · University of Virginia
Answered on

Locally advanced prostate cancer remains a significant clinical challenge. The role of "adjuvant" docetaxel to follow patients receiving primary radiotherapy plus ADT has been tested in at least 5 randomized studies, with RTOG 0521 the only one to my knowledge showing survival benefit (albeit a small one). In this study 2 years of ADT was used. The setting in which the question was asked radical prostatectomy followed by adjuvant radiotherapy plus docetaxel to my knowledge has not been tested pr...

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