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In patients with suspected or confirmed IgG4-related disease, how should clinicians evaluate and manage potential coronary artery involvement?

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Related Questions

When evaluating a patient with IgG4-related disease, are there particular exposures or risk factors you routinely ask about during the history to help identify potential contributors?

How do you approach management of a patient with a retroperitoneal soft tissue mass and elevated IgG4 level when tissue biopsy is not feasible?

In a patient with prior biopsy-proven IgG4-related pachymeningitis who develops recurrent neurologic symptoms years after discontinuing immunosuppression, how do you determine whether this represents relapse versus alternative etiologies?

How would you approach a patient with history of cocaine use presenting with chronic sinusitis and acute vision loss from an extensive inflammatory changes in the sinus and orbit compressing the optic nerve with negative ANCA, inconclusive nasal biopsy and elevated serum IgG4?

What clinical features would raise your suspicion for IgG-4 related disease?

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