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In postmenopausal osteoporosis, would you switch to romosozumab (rather than a PTH/PTHrP analog) if a patient fractures while on denosumab?

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What would your sequence of treatments be for patients who sustain a fracture while using denosumab and are good candidates for escalation to romosozumab?

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1 Answer
Mednet Member
Mednet Member
Rheumatology · NYU Langone
Answered on

This is an interesting question because it raises the subject of how one defines "treatment failure" among patients who are using bone-strengthening medications. I remind patients that our drugs are most effective at preventing spinal fractures with efficacy that can exceed 70% relative risk reducti...

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