In pregnant liver transplant recipients, which transplant-specific modifiable targets do you prioritize to reduce prematurity and fetal growth restriction?
1 Answer
Mednet MemberInvited Expert
Hepatology · University of California, Los Angeles
Answered on
There is no data or guidance on how to reduce prematurity or fetal growth restriction in transplant recipients.
However, regarding this patient population, the AASLD Practice Guidance on Reproductive Health summarizes the key points nicely of what's recommended in liver transplant recipients planning pregnancy.
- Mycophenolic acid products are contraindicated in pregnancy and lactation, and contraceptive agents with low failure rates should be used.
- Pregnancy should be delayed until at least 1 year after transplant, and with greater than or equal to 6 months of stable graft function.
- CNIs, azathioprine/6-MP, and corticosteroids are acceptable for use in pregnancy and lactation.
- mTORs are not recommended in pregnancy or lactation due to a lack ...
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