In settings where alcohol use is commonly underreported, what is your preferred practical approach to reduce MASLD vs ALD misclassification in routine hepatology or primary care (structured AUD screening, targeted alcohol biomarkers such as PEth/EtG, or a combined attribution algorithm), and how do you operationalize it without undermining patient engagement?
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Hepatology · Penn State College of Medicine
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My practical approach is a combined strategy: routine use of a structured alcohol assessment (AUDIT-C) alongside metabolic risk profiling, with targeted use of objective biomarkers such as PEth when the reported alcohol history is uncertain or discordant with the clinical picture. I frame these asse...
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