In those patients who are initiated on omalizumab for multiple food allergies, once baked egg and baked milk are introduced into the diet, do you rely upon skin prick testing and/or ImmunoCAP testing in order to make the decision to introduce prepared egg or whole milk into the diet?

When the patient is on omalizumab, neither skin prick testing or serum IgE testing would be reliable biomarkers to follow.

Omalizumab is known to reduce (not necessarily eliminate) skin prick responses.

Ledford, PMID 30819523

In the short term, serum-specific IgE may even increase prior to a possible ...

While the precise answer is unknown, there is considerable data that is relevant.

In the prior studies, Xolair (omalizumab) was administered anywhere from 12 to 20 weeks before food challenges were performed.

For example, and the most recent studies that led to FDA approval of using Xolair to treat ...