In what clinical situations do you consider azathioprine for treatment of inflammatory arthritis?

Azathioprine (AZA) is among the oldest pharmacologic immunosuppressive agents in use today. Initially developed as a long-lived prodrug of 6-mercaptopurine (6-MP), it was quickly found to have a more favorable therapeutic index.

Gertrude B. Elion (Winner of 1988 Nobel Prize in Medicine for “importa...