In what situations do you utilize G-CSF in germ cell tumors or Hodgkin lymphoma patients receiving bleomycin?

Having been both a lymphoma doctor and germ cell tumor doctor, I can tell you our experience. The current standard for poor risk germ cell tumors is to routinely include G-CSF with BEP X 4 and VIP X 4 in most high volume centers. A number of experts include growth factors routinely in good risk pati...

I will limit my comments for patients with germ cell tumors.

Bleomycin containing combination regimens, such as BEP, are associated with intermediate (10-20%) risk of febrile neutropenia. Poor-risk germ cell tumor patients who receive higher-dose/intensity combination chemotherapy (such as 6 cycles o...