In what situations, if any, is it appropriate to forego surgery for nodal recurrence (intraparotid and/or ipsilateral neck) of cutaneous SCC and definitively treat with chemo-RT?

I would consider definitive chemoradiation therapy if a patient was medically inoperable or the cancer was surgically unresectable. Otherwise, I would advocate for therapeutic lymphadenectomy, and usually, adjuvant radiotherapy, unless the pathologically evaluated nodal disease was low risk (only on...

When a gross total resection is not possible.