In which scenarios do you stage breast cancer using CT and nuclear bone scans versus PET-CT?

Topics: Breast Cancer • Radiation Oncology • Medical Oncology • NCI-CCC Tumor Board Question • Yale • NCI-CCC Breast Tumor Board Question • Breast Cancer, Metastatic • Breast Cancer, Non-metastatic

Answer from: Medical Oncologist at Academic Institution

In a recent study (Dayes et al., PMID 37235845), systemic staging with FDG PET-CT more frequently changed the clinical stage from IIB or III breast cancer to stage IV disease (23% metastases detection rate) than staging with CTs of the chest, abdomen, pelvis, and a bone scan combined (11% metastases...

Comments

Radiation Oncologist at South Sacramento Medical Center
Can you get your radiologists to include limbs and...

Medical Oncologist at Locum Tenens
Great review!

Medical Oncologist at Carson Tahoe Health
Is there now a role for ctDNA in staging breast ca...

Medical Oncologist at St Lukes Cancer Care Assocs
Clinically relevant information. Thank you.

Medical Oncologist at The Everett Clinic - Providence Regional Cancer
Great summary and review!

Answer from: Medical Oncologist at Community Practice

Agree that oligomet met dz is often biologically distinct. For TNBC/Her2+/high grade disease, I’d get PET/CT, whole body if you like. If oligomets are found then aggressive systemic therapy then if response, proceed with locoregional and consider definitive treatment (e.g., RT) to oligomet sit...

Answer from: Medical Oncologist at Community Practice

PET CT accomplishes staging in most patients and requires just one test and no IV or PO contrast other than the isotope--easier on patients.

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