Is 10 Gy x 5 an acceptable dose to use for lung SBRT in tumors with favorable location (eg. not central and not encroaching on the chest wall?)

The paper cited, which my colleague Kevin Stephans authored, used our large institutional data base with long term follow up to carry out a retrospective review of BED adjusted SBRT schedules and showed no difference in overall survival, but slightly improved local control, with higher BED schedules...

I agree except that for favourably located tumours, I still use 18Gy X3. For locations near the ribs, near main airways I will use 10GyX5 if I cannot meet the restraints based on protocols. Size matters. Bigger the mass, the higher the dose we need as demonstrated by the long term data from Japan th...