Is a larger prostate size or volume associated with a higher absolute PSA bounce after radiation?

In a patient with a >100 cc prostate treated with radiotherapy alone, would you be concerned about a roughly 2 ng/mL rise in PSA less than 12 months after treatment?

Answer from: Radiation Oncologist at Academic Institution

I have not seen anything in the literature to indicate that the magnitude of the PSA bounce is related to prostate size, but it's certainly possible. The highest bounces I have seen after treatment were in patients treated with LDR brachytherapy (my personal record is 8 ng/mL, and it eventually beca...

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Radiation Oncologist at Genesis Healthcare Partners- San Diego
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Is a larger prostate size or volume associated with a higher absolute PSA bounce after radiation?

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