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Is ATM a contraindication to radiation therapy?

Published data show a mixed review of late toxicity with adjuvant radiation. What are guiding principles we should use as more patients are getting genetic testing? https://www.ncbi.nlm.nih.gov/pubmed/11849780 https://www.ncbi.nlm.nih.gov/pubmed/11710885 https://www.ncbi.nlm.nih.gov/pubmed/17517479 https://www.ncbi.nlm.nih.gov/pubmed/14643952 https://www.ncbi.nlm.nih.gov/pubmed/16338099
1 Answer
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

The data is limited with some concern about increased late efffects including fibrosis and increased risk of contralateral breast cancer caused by RT. I have not used this as absolute contraindication but discussed pros and cons with few patients I have treated and taken all measures to reduce contr...

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