Is concurrent administration of intraocular Avastin for macular degeneration a concern when planning SBRT for lung cancer?

I am currently treating a patient who received intraocular Avastin a week prior to starting SBRT. I tried to post it but your question was received a little earlier! For my patient, intraocular dose was 1.5mg vs. a normal systemic dose of 5-10mg/kg. So likely at least 2 orders of magnitude less assuming all the dose ends up systemic, although reportedly very little leaks into circulation. We decided the dose was negligible. Hopefully, we are right!