Is febuxostat a safe alternative for patients who are HLA-B*58:01 positive and of Han Chinese descent?

Cutaneous reactions to allopurinol range from the mild to the very severe and life-threatening such as Stevens-Johnson's Syndrome (SJS) and toxic epidermal necrolysis. The association of these reactions is so strong as to have its own acronym, AHS, for the allopurinol hypersensitivity syndrome.

These...