Is is okay to offer SBRT for central lung tumors in direct contact with the esophagus?
If so, 50 Gy / 5 fx? 7.5 Gy / 8 fx? If so what dose constraints would you use to help determine fractionation?
2 Answers
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan Kettering Cancer Center
Answered on
My short answer is: probably not, if you are considering standard regimens like 10Gy x 5. The risk of fistula appears to be significant if you expose the esophagus to full prescription dose. My group described two patients receiving lung SBRT who developed significant esophageal complications (fistu...
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Mednet MemberInvited Expert
Radiation Oncology · Cleveland Clinic
Answered on
I appreciate @Dr. First Last's thoughtful response. In response to the question and based on our own data published by my Cleveland Clinic colleague @Dr. First Last [Esophageal dose tolerance to hypofractionated stereotactic body radiation therapy: risk factors for late toxicity., Int J Radiat Oncol...
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