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Is it appropriate to offer low dose radiation for Hidradenitis Suppurativa that have failed conservative interventions?

What dose and field margins would you add? Is a 50% response rate realistic to counsel a patient? What would you quote as a realistic rate for secondary cancers when treating an older patient to 7.5 Gy just to the skin?
1 Answer
Mednet Member
Radiation Oncology · The University of Oklahoma College of Medicine
Answered on

We are currently writing about our experience with high dose electron therapy for HS. Low dose therapy was not giving us the results we wanted. The dose needs to be high enough to destroy the sebaceous glands where the chronic infection resides. Our initial treatment is 3 Gy fractions 3 times per week to 45 Gy to fields covering the entire area of HS. pockets of resistant diseases recieve an additional 15-30 Gy as needed.

The results have been very good in our series. Complete results will be submitted for publication this fall.

I would think the odds of secondary malignancy in older patients is negligible.

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