Is it ever safe to use a biologic DMARD in a patient with RA who is on suppressive antibiotics due to a history of septic prosthetic arthritis?
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In a patient with chronic joint prosthesis infection requiring chronic suppressive antibiotics which biologic would you consider?
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2 Answers
Mednet MemberInvited Expert
Rheumatology · U.S. Department of Veterans Affairs
Answered on
I have used Orencia and HCQ as more immunomodulating with suppressive M/W/F antibiotics in a patient with UTI/Bactrim.
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Mednet Member
Rheumatology · Rheumatology Associates of Long Island
Answered on
I think the key is the use of long-term/lifelong antibiotics, vigilance regarding infection activity, the specific choice of biologic/immunosuppressive/immunomodulatory medication, and also having the appropriate discussion with the patient and the consulting infectious disease physician.
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